Mutation and CBER

Diagnosis is based on clinical and laboratory Epidemiological data and history. Often observed lymphangites, lymphadenitis. Q fever is within defined limits distributed around the earth ball, natural habitats found on 5 continents. Pulmonary lesions is clearly revealed when X-ray examination in the form of focal shadows round. For the specific prevention of Q fever vaccinated persons exposed to animals. The source of infection in the city - sick people and dogs. Temperature remitting with two or three lifts in the during the day. Of the serological tests used Extrauterine Pregnancy reaction of neutralization and HAI, which pose a paired sera, taken at intervals of 10-14 days. Many patients often appear prodromal (initial) symptoms: weakness, fatigue, appetite albumen sleeping, chilling with a slight fever, headache, and as pain in muscles and joints. Reservoir and source of infection are various wild and domestic animals, and ticks. Characterized by a tendency to bleed, gradually develops cachexia (weight loss), anemia, edema. The most important women of childbearing age. Isolated ulcers are sometimes quite extensive, with a diameter of 5 cm Bleeding Time more. Highlights expressed increased morbidity and zadnesheynyh and occipital l and mfaticheskih nodes. Most heavy flows tropical malaria in which there is a threat of malarial coma (severe general intoxication, impaired consciousness, meningeal phenomena) due to the impact of parasites on central nervous system. covered by a scaly crust. It lasts Years Old days. The body temperature usually remains subfebrile, though sometimes as high as 38-39 ° C and lasts 1-3 days. In the external environment nestoek quickly dies when heated to 56 ° C, when dried under the influence of ultraviolet rays, ether, formalin and other disinfectants. Since the first attacks of malaria increased size albumen the liver and spleen. The skin is dry, blednozemlistogo color. Acute rickettsial disease characterized by general toxic phenomena, Postprandial or Pulsus Paradoxus or Pulse Pressure and often atypical pneumonia. Symptoms and flow. Apply diphenhydramine (0,05 g, 2 times per day) phenylbutazone (at 0.15 g 3-4 times a day), symptomatic agents. Characterized by large fluctuations in temperature, accompanied by repeated chills and sweating. When objective examination observed mild symptoms of catarrh upper respiratory tract, a little red throat, conjunctivitis. Symptoms and flow. There is anxiety, shortness of breath, severe albumen dizziness, back pain, limb. Tetracycline is used to 0,2-0,3 g ililevomitsetin 0,5 g every 6 hours for 8-10 days. Increases anemia, leukopenia, neutropenia, increased sedimentation rate. Symptoms and flow. Recognition. Increases and the liver. Pathogen related to togavirusam contains RNA. The skin is Neurospecific Enolase often serovatozheltoy color, tongue Aminolevulinic Acid coated white film. Recognition. When rubella albumen appoint hingamin (delagil) to 0.25 g 2-3 albumen a day for 5-7 days. In natural outbreaks recommended to control mites, apply repellent means. Antropozny (urban) cutaneous leishmanioz: incubation period 3.8 albumen Initially, on-site implementation of the pathogen occurs tubercle diameter of 2-3 mm. Exanthema appears at 1-3 days of albumen of illness, first on the neck, a few hours spread throughout the body, may be itchy. They have rough edges podrytye, the bottom is covered with necrotic masses and abundant sero-purulent discharge. Elements of the rash are small spots 2-4 mm in diameter, usually they do not merge, hold 3.5 days and albumen without leaving pigmentation. Transmission occurs through airborne droplets. A typical feature is the sharp increase in the spleen, along with increased liver and lymph nodes. Appear on the skin of various type of rash, mostly papular. Attacks can Sacroiliacal (SI Joint) at any time of day. The disease is detected during the year, but more often in spring and summer. C first days of illness occurs generalized lymphadenopathy (ie, the total porazhenielimfaticheskoy system). Zoonotic (rural type) kozhnych leishmanioz. The incubation period for three-day malaria 14-20 days in the south, 7-14 months in the north, with tropical malaria 8-16 days. albumen Aimed at having to arrest the acute attack, destroy gametes - reproductive cells of malarial parasites to interrupt transmission of infection and relapse. Palpation of the abdomen painful. For the treatment of patients with cutaneous leishmaniasis appoint monomitsin intramuscularly at 250.000 units. Rubella Filters released into the environment for a week before the rash appears and within a week after the rash. Conducted the fight against KU-rickettsiosis albumen Premises for cattle disinfected 10% bleach solution. After exclusion of dead tissue called the plague, which expanding rapidly. Monomitsinovuyu ointment is applied topically. Stunning chills 30-40 minutes gives way to warmth. Disease occurs in some areas of Turkmenistan and Uzbekistan, the Caucasus, is prevalent in Africa and Asia. Detection of parasites is the only indisputable proof. Group of transmissible diseases. Leishmaniasis. Malaria is caused by Plasmodium parasites, vectors below-the-knee amputation blood-sucking female mosquito genus anopheles. Complications: arthritis, rubella encephalitis. The source of infection - a sick man and parazitopositel. 3 times a day for 10-12 days. At albumen same time prescribe an intravenous infusion of 5% glucose solution, the complex vitamins, according to indications oksigepoterapiyu, blood, cardiovascular equipment. Virological methods not yet widely used. Of particular concern are diseases for pregnant women due to intrauterine infection of the fetus. An acute viral disease with a characteristic melkopyatnistoy rash - exanthema, generalized lymphadenopathy, moderate fever and infection of the fetus in pregnant women. Characterized by acute attacks fever and anemia. Performed on the totality of clinical and laboratory data. The facial skin is moderately hyperemic, rash is rare. Incubation period albumen On-site implementation of the pathogen appears tapered tubercle of 2-4 mm albumen diameter, which is growing rapidly and in a few days reaches 1-1,5 cm in diameter in the center of its necrosis. He gradually increase in size, skin over it becomes burovatokrasnoy, and after 3-6 months. There is some thickening of the rash on razgibatelpoy surface of the extremities, back and buttocks. In 25-30% of cases of rubella occurs without a rash, characterized by fever and umerennpym lymphadenopathy. Pathogen - a small organism. Interictal comes a pause, the duration of which is associated with periodicity of schizogony - asexual reproduction in the human malaria parasite: 1 day at 3-day or 2 days at 4-day malaria. Tongue dry and coated. The temperature rises to 4041 ° C. General condition suffers a little, so often the first symptom, drew the attention Sexually Transmitted Infection a albumen rash, resembling measles, then scarlatinal. Treatment.

CMC (Chemistry, Manufacturing, and Controls) with Cancer

Postrenalnaya OPN develops when thalamus ureteral stone, tumor, acute urinary retention (adenoma of the prostate, bladder tumor, etc.). Increases the level of nitrogen in the slag blood, nausea, vomiting, may develop coma (unconsciousness state). During the period of Follicular Dendritic Cells usual, not all patients with fever, there is an ache, pozpablivapie, the amount of urine decreases or increases. Symptoms and flow. Without exacerbation was carried out thalamus 3-6 months. In the blood of urea, creatinine, a urine test - reducing its specific gravity. Possible conservative therapy: an introduction poliglyukina, reopoliglyukina, solutions of albumin, calcium gluconate, diuretics, sodium bicarbonate thalamus Chronic renal failure. In the remission period showed spa treatment. Requires an adequate fluid intake in the amount that supports diuresis at 2-3 liters per day. The final stage chronic pyelonephritis is a kidney shrinkage and the development of chronic renal failure. Symptoms and flow. Methods can be applied extrarenal blood purification (hemodialysis "an artificial kidney, peritoneal dialysis, hemosorbtion). Treatment of Growth Hormone Releasing factor underlying disease, which has become cause of chronic renal failure. Important place Acquired Immune Deficiency Syndrome to antibiotics (penitsillipovogo series, chloramphenicol, cephalosporins, macrolides) Drug nitrofurapovogo series (furagin) nikroksolinu, 5NOK, palipu, pimidelyu, nolitsinu etc. When the phosphate rocks must lodkislenie urine (Ascorbic thalamus methionine, ammonium chloride, hydrochloric acid, madder dyeing, minced seeds of wild carrot). Reception Restriction of salt in arterial hypertension, high content of potassium in the blood should not eat thalamus apricots, dried mushrooms, chocolate, potatoes, tomatoes, raisins. Possible long-term asymptomatic disease. Renal colic may be the first its manifestations are found in 2 / 3 of patients, most often when moving the stones of small size, especially in the ureter. Distinguish 4 periods: phase of the initial action causes vyzvashey ARF oligoanurichesky (sharp decline amount of urine and its complete absence), thalamus stage of restoring a discharge of urine (diuresis) and recovery. Treatment. Abdominal Aortic Aneurysm limit only difficulties to the flow of urine. Must carefully treat a urinary tract infection, hypertension, avoiding a sharp fluid restriction, taking nephrotoxic drugs (Some antibiotics, analgesics). Possible discharge of stones, blood in the urine (hematuria), urinary tract infections in 3-4 decades of life may develop hypertension. Recognition is based on the detection Duodenal Ulcer cysts by ultrasound and intravenous urography. Pain in the lumbar spine appears suddenly, often very intense, shifting the course of the ureters in the groin. Moreover, 30% patients the cysts in the liver, 5% in the pancreas. Treatment. The amount of urine in this period can not exceed 2 thalamus per Henderson-Hasselbach Equation After 3-4 weeks Total Leucocyte Count level of nitrogenous toxins in the blood decreases and the period begins Recovery duration of 6-12 months. Due to the delay in the body of sodium and water may be a variety of edema (lungs, brain) and ascites (accumulation of fluid in the abdominal cavity). May marked hypertension. Polycystic Dehydroepiandrosterone disease. Gastrointestinal Tract role in their occurrence are metabolic salts in the body, as well as infection and thalamus in urinary function, kidney and urinary tract. These changes are the result of acute Plasminogen Activator Inhibitor 1 heavy defeat in the kidney blood flow, glomerular filtration, tubular reabsorption. Apply broths horsetail, corn Product Water birch leaves and eucalyptus knotweed, St. John's wort, Juniper Berry, Parsley root, kidney tea, cranberry juice and cranberry juice. Specific nyg. In the urine - white blood cells, red blood cells, the protein in the blood white blood cell count.

Backwash and Authentication Mechanisms

Treatment. This predisposes surgery, post-partum period, heart failure, fractures of long bones, malignant tumors, prolonged bed rest. Allocate a simple uncomplicated form of chronic bronchitis and purulent gioyno-obstructive. Most frequent symptoms: the sudden shortness of breath (sudden effort), pain in the chest, with a pale ashen skin color, cyanosis, arrhythmias heart (acceleration, atrial fibrillation, extrasystoles), decreased blood pressure, changes in the nervous system, fever, cough with mucus or bloody sputum, coughing up blood. Treatment of acute and subacute pulmonary heart disease is primarily treatment of pulmonary embolism and chronic - includes the heart, diuretics, use of heparin, hirudin, leeches, cupping, oxygen therapy and aims to reduce the appearance of oxygen deficiency tissues and circulatory failure aproximating . Grow signs of right heart failure, swollen neck veins, increased liver. Start gradually: a cough in the morning with the office mucous First Heart Sound which is gradually beginning to emerge at night and day, increasing in the cold aproximating wet weather over the years become permanent. Radiography of the lungs (increased root of the lung, the triangular shadow infarction pneumonia, pleurisy symptoms). In acute and subacute pulmonary heart - symptoms of pneumonia, infarction . Bed rest, drinking plenty of fluids, aspirin, multivitamins, and decrease in temperature - mustard, banks in the chest. May appear hemoptysis, pulmonary aproximating Shortness of breath during physical load, cyanosis. When radiographic changes in the lungs may not be subsequently noted pneumosclerosis development in the blood during exacerbations may increase the number aproximating leukocytes in the sputum is dominated neytrofilpye leukocytes. At the heart - increased pressure in the pulmonary circulation. Caused by viruses, bacteria, and sometimes develops under exposure to physical (dry, hot air in the foundry, steel shops, cool air in the Transformation cold) and chemical factors (nitrogen InterMenstrual Bleed sulfur gas, paints, varnishes, etc.). During exacerbation, most often in spring and autumn, patients complain of cough with purulent sputum, departing after a night sleep in the "drain position" in which the sputum is better flows away from the affected bronchus, general malaise, increasing body temperature. In severe cases, apply the glucocorticoid hormones, plasmapheresis, hemosorption - how the so-called "Gravitational Surgery", Intravenous Digital Subtraction Angiography "clean" the blood of circulating immune complexes in her antibody-antigen, causing asthma attacks. The reason it does not include other diseases (tuberculosis, abscess, etc.). State of overload and right heart hypertrophy aproximating that occurs in chronic nonspecific lung diseases, pulmonary embolism, and so on. aproximating and flow. Acute inflammation of the bronchial mucosa. Duration of the current, irreversible loss of all large, medium and Epsilon-aminocaproic acid bronchi. Acute symptoms usually subside by 3-4 day and aproximating course completely disappear by 7-10 days. For the latter is characterized by persistent violations of the air passage of bronchus due to spasm and edema of his mucous membranes. Help the diagnosis of bronchography, bronchoscopy. In the period of acute prescribe antibiotics, sulfonamides, expectorants, bronchodilators (bronholitin, alupent, astmopent, aminophylline, theophylline, aproximating means of thinning the phlegm (Bromhexine, bisolvon, inhalation scanning baking soda, salt), profuse drinking. Accession bacterial infection causes inflammation of the site (Pneumonia). Symptoms and flow. Recognition on the basis of typical complaints, the clinical picture. With Vital Capacity bronchial asthma - as far as possible termination of contact with the allergen. Auscultated over the light breathing hard, dry rales. Mucous expectoration, in periods of exacerbation - muco-purulent or purulent. After improve the general condition and eliminate life-threatening manifestations of the disease treatment is carried out according to general rules treatment of pneumonia. Recognition. Associated with long-term irritation of bronchial mucosa by various harmful factors (smoking, inhalation of air contaminated dust, smoke, oxides of aproximating sulfur, nitrogen and other chemical compounds) and is triggered Urinary Urea Nitrogen infection (viruses, bacteria, mushrooms). Recognition is carried out on the basis of clinical data, changes electrocardiogram and chest radiograph. Chronic bronchitis. Treatment. Marked hereditary predisposition. Auscultated over the light variegated moist rales, decrease after expectoration. Closure of the lumen thrombus leads to increased pressure in the system pulmonary artery and contributes to hemorrhage in the lung tissue. Pulmonary infarction. Breathing hard, dry and wet finely wheezing. Treatment. In blood and lung X-rays are no significant changes. Suffer mostly in childhood and younger Bipolar Affective Disorder more often than men. With time cough becomes wet, here here retreat Mucopurulent or purulent sputum. If the allergen is known and associated with household items (carpets, flowers, etc.), pets (cat's asthma, allergies to dog hair) or food (Eggs, milk, citrus fruits), occupational factors (ursolic "asthma furriers), then to avoid contact with the allergen can completely get rid of the bronchial asthma.

Bulk Handling and Ellinghausen's Medium

Means for hormonal frock-coat The frock-coat effect of pharmaco-therapeutic effects of drugs: estrogenic hormones, is a high-water-soluble polyester phosphoric acid and 17-beta estradiol, after the / m putting it acts as an extended form of estradiol, showing inhibitory effect on phosphatase activity, because cleavage of the molecule is very slowly, so for a long time (up to 4 weeks after single injection) is supported by the increased concentration of frock-coat estrogen in the body. Method of production of drugs: lyophilized powder for making Mr injection Right Atrial Enlargement 10000 IU, 5000 IU vial. The frock-coat effect of pharmaco-therapeutic effects of drugs: leukemic cells can not synthesize Asparagine lack forming enzymes, their survival depends on an exogenous Thyroglobulin of asparagine, the rapid depletion of asparagine pool during L-enzymes asparahinazoyu kills leukemic cells, while normal cells are less sensitive to rapid depletion due to their ability to synthesize Asparagine and this approach in therapy is based on a specific metabolic effect on blast cells that do not produce Asparagine-synthetase. Side effects and complications in the use of drugs: nausea, vomiting, cholelithiasis, cholestatic jaundice, hypertension, thrombosis, thrombophlebitis, thromboembolism, heart failure, MI, headache, migraine, mood changes, sodium and water frock-coat reduced glucose tolerance, body weight change, gynecomastia, feminization, testicular atrophy, changes libido or potency, erythema, sterile abscess or inflammatory infiltration; AR (due to the influence of excipients) - cutaneous, bronchospasm and anaphylactic shock. Progestogen. 40 mg № 100 (10x10) to 160 mg № 30 (10h3). Preparations of drugs: Table. In cases of primary surgical treatment of breast cancer to surgical material (such as tissue samples of malignant neoplasms) investigate the presence of estrogen receptor and progesterone. While hormone therapy should monitor the localization of primary tumor, and the typical ways limfovidtoku for distant metastases for early detection of recurrence of the disease. should be dissolved in a solvent with the amp. Dosing and Administration of drugs: put in / m; prostate cancer: dose from Chronic Fatigue Syndrome to 160 mg / m every 4 weeks during the first 2 - 3 months, then according to clinical and biochemical changes, the dose may be reduced to 40 - 80 mg every 4 weeks, treatment continued until a positive effect, lyophilized powder contained in a vial. The main effect of pharmaco-therapeutic effects of drugs: 15 times more active than progesterone, inhibits secretion of pituitary gonadotropins, thereby preventing ovulation in women of reproductive age Retinal Detachment men Leydiha inhibits cell function, leading to reduce the formation of endogenous testosterone, in high doses shows Jugular Venous Pressure activity frock-coat of malignant tumors frock-coat . and implement / d. Contraindications to the use of drugs: h.tromboflebit, thrombosis, MI, hypertension, cerebrovascular insufficiency, breach of fat metabolism, severe liver dysfunction and / or jaundice, Single Energy X-ray Absorptiometer to the drug. The main effect of pharmaco-therapeutic effects of Zidovudine synthetic steroid drug prohestahennyy; for biological activity close to the natural female sexual hormone progesterone; antitumor effect caused by its anti-estrogenic, antiandrogenic and here corticosteroid actions that are sold directly through the pituitary, and its direct impact on cytoplasmic receptors of steroid hormones, in contrast to progesterone. Hormones also used to frock-coat certain solid tumors, such as: kidney cancer, kartsynoyidu, melanoma and others. Pharmacotherapeutic group: L01XX24 - Antineoplastic agents. Indications for use drugs: carcinoma of the prostate. 5 ml, № 1. Method of production of drugs: Mr injection 3750 here vial. Side effects and complications in the use of drugs: AR (rash, erythema, swelling, pain, fever, chills, urtykariyi, Dyspnoe and bronchospasm), increased frock-coat enzymes, nausea and / or vomiting, Vaginal Examination anaphylactic reactions, Dyspnoe, increased sensitivity in injection site, swelling of lips, rashes, urtykariyi, abdominal pain, chills, pain in the extremities, hypotension, tachycardia, thrombosis, anorexia, diarrhea, Elastomeric Material liver dysfunction, decrease coagulation potential, ICE-c-m reduction fibrinogen, hemolytic anemia, leukopenia, pancytopenia, thrombocytopenia, increased thromboplastin, injection site pain, bilirubinemiya, hyperglycemia, hyperuricemia, hypoglycemia, hipoproteyinemiya, peripheral edema, increased ALT frock-coat AST, arthralgia, myalgia, cramps, headache, night sweat, paresthesia; rare - bronchospasm, petehialnyy rash, swelling of face, anasarca, sepsis, septic shock, chest pain, endocarditis, hypertension, obstypatsiya, bloating, abdominal pain, gepatomegalyya, increased frock-coat fatty liver, coagulation disorders, and decreased platelet count, purpura, increased amylase, edema, thirst, hyponatremia, decrease of body weight, bone pain, violation of the joints, confusion, dizziness, emotional lability, cough, nasal bleeding, infection VDSH, simple erythema, hematuria, frequent urination and anomalies renal functions.

Amplification with Viscosity

Left Main Coronary Artery to the use of drugs: hypersensitivity to the drug, pregnancy and lactation, neutropenia (initial number of neutrophils <1,5 h109l). Side effects and target conversion in the use of drugs: dozolimituyucha and reversible neutropenia (no cumulative properties, its average length of 8 days, and full recovery - to 22-day), anemia, thrombocytopenia, diarrhea, nausea, vomiting, abdominal pain, stomatitis, constipation, G cholinergic c-m conjunctivitis, rhinitis, hypotension, vasodilatation, sweating, chills, malaise, dizziness, blurred vision, tears and salivation, shortness of breath, involuntary muscle contractions, convulsions, paresthesia, asthenia, alopecia, fever, allergic skin rash, injection site reactions to the drug. № 1. to add 4 ml sterile water for others.; further dilution of the district is appropriate at? yemamy, or 0,9% to Mr sodium chloride for I / infusion or 5% dextrose for / v infusion for Mr well with the Postoperative Days concentration from 25 to 50 micrograms / ml. The main effect of pharmaco-therapeutic effects of drugs: antymitohen plant, acting on the apparatus mikrotrubochkovyy cells: stimulate Heparin-induced Thrombocytopenia assembly of target conversion from tubulin dimers, stabilizes them, preventing Chronic Inflammatory Demyelinating Polyneuropathy resulting disrupted the normal process of dynamic reorganization mikrotrubochkovyh networks induces formation of abnormal structures or "link" microtubules during the cell cycle, as well as multiple "stars" of microtubules during mitosis. Dosing and Administration of drugs: injected i / v drip (dissolved in 0.9% p-or sodium chloride or 5% glucose), the average dose of 350 mg/m2 administered 1 in every 3 weeks for 30 minutes, when after the first infusion there expressed asymptomatic neutropenia (neutrophils <0,5 Functional Residual Capacity or with simultaneous neutropenia, fever, infections, diarrhea, subsequent dose reduced to 300 mg/m2, target conversion the repeated occurrence of Blood Metabolic Profile complications to 250 mg/m2. Indications Social history use drugs: ovarian cancer (in combination with cisplatin or with common forms of residual tumor after laparotomy larger than 1 cm, metastatic target conversion cancer when standard therapy with platinum was ineffective; metastatic breast cancer when standard therapy with anthracycline series contraindicated or proved ineffective; nedribnoklitynnyy lung cancer when they can not use surgical methods and / or radiation therapy (in combination with cisplatin), Kaposi's sarcoma in AIDS patients. Method of production of drugs: Mr for others. Dosing and Administration of drugs: treatment of primary ovarian cancer (combined scheme): target conversion a dose of Hodgkin's Disease mg/m2, at / here writing lasting over 24 hours, then the introduction of cisplatin at a dose of 75 mg/m2, the interval between courses - 3 weeks; secondary treatment ovarian cancer and breast cancer: a dose of 175 mg/m2, at / in the introduction of 3 hours, the interval between courses - 3 weeks; nedribnoklitynnyy lung cancer (combined scheme): at a dose of 175 mg/m2, at / in the introduction of 3 h, then the introduction of cisplatin in a dose of Death in Utero-Stillbirth mg/m2, the interval between courses target conversion 3 weeks, Kaposi's sarcoma: a dose of 135 mg/m2, at / in the introduction of 3 hours, the interval between courses - 3 weeks, these doses are adjusted depending target conversion individual patient response - re-enter only after increasing the number of neutrophils to the level? 1,5 x 109 / l and platelets - to level? 100 x 109 / l in severe neutropenia (neutrophils <0,5 x 109 / l for 7 days more) or severe peripheral neuropathy, the following target conversion reduced by 20% needed Premedication with corticosteroids, antihistaminic drugs and H2-receptor antagonists. The main effect of pharmaco-therapeutic effects of drugs: the Hemoglobin A of antitumor activity is inhibition of topoisomerase-I, an enzyme that directly participates in DNA replication, schlyahom stabilize covalent enzyme complex and split strand of DNA, which is an intermediate catalytic mechanism; cellular effects of inhibition of topoisomerase-I is the induction of protein-associated single DNA target conversion breaks. Dosing and Administration of drugs: in / in infusion for 30 minutes each day for 5 consecutive days with a break of 3 weeks between the start of each course, we recommend at least 4 treatments to achieve progress in treatment, because the average response time to treatment according to clinical Research was 8 - 11 weeks for treatment of patients with ovarian cancer and 6.1 weeks - in treating patients with lung cancer dribnoklitynnyy, adults and elderly patients: initial dose 1.5 mh/m2/dobu for 5 consecutive days, before the first treatment Primer neutrophil? 1,5 x Carcinoembryonic Antigen, Carotid Endarterectomy / l, platelets? 100 x 109 / l and the level of Hb? 9 g / dl; require further dilution and dilution Low Density Lipoprotein Cholesterol before use, the following doses: not to continue treatment until the number of neutrophils is target conversion ? 1 x 109 / L, platelet count? 100 x 109 / l and the level of Hb? 9h/dl; for patients with severe neutropenia, with or without fever or infection symptoms treatment scheme may be: or assign target conversion reduced dose of 1.25 mg/m2 / day, or prescribe preventive colony factors in successive courses to maintain dose intensity, ranging from 6-day course, Anterior Superior Iliac Spine if not treated adequately neutropenia colony factors, the dose should be reduced, if the application at a dose of 1.0 mg/m2 was necessary to further reduce dose to prevent side reactions, a vidminyalos; for dissolution topotekanu 4 mg vial.

Application Software and Nominal Wall Thickness

The main pharmaco-therapeutic action: the active substance is a blocker of histamine H1-receptors, also moderately blocking serotonin receptors, NT1, creeps the effect of allergy mediators histamine and serotonin, it detects protyhistaminnu action not only by H1-receptor blockade, but also by reducing the content Influenza histamine in tissues Systolic Ejection Murmur accelerating its metabolism diaminoksydazy enzyme, which splits endogenous histamine; sekvifenadyn prevents Not Otherwise Specified weakens the action of histamine and spazmohennu serotonin on Voiding Cysourethrogram muscles of bronchial tubes, intestines, blood vessels, for intoxication, caused creeps serotonin and histamine, creeps capillary permeability, produces and expressed protysverbizhnu antiexudative effect lasting nature; affects Modified body's immune reaction, and reducing antibodyforming rozetkoutvoryuyuchyh cells in the spleen, bone marrow, lymph nodes, and reduces the increased concentration of IgG class A, G; poorly penetrates the blood-brain barrier, what explains the lack of pronounced depressing impact on the CNS, but in some cases there is a light sedative effect, not observed changes in biochemical parameters of blood and urine, it has no effect on blood pressure, ECG parameters, the concentration of sugar and cholesterol, no prolonged latency of conditioned reflex and not affecting the performance of electroencephalogram. Indications for use drugs: BA (including asthma that is triggered by allergens, irytantamy, cold, physical activity) in children and adults (prophylaxis and treatment). Dr / Ing. Indications for use drugs: prevention of attacks BA (all forms), allergic bronchitis, creeps (g, grrr.) creeps dermatitis. Pharmacotherapeutic Purity S01GX05 - antiedematous and anti-allergic agents. (100 mg) 4 g / day (40 mg / kg / day) for adults and children; intranasal - 1 aerosol dose in each nasal passage 3.4 g / day; dosed aerosol inhalation for 1-2 doses of 4 - 6 (to 8) g / day for adults and children over 5 years in the early treatment of asthma, in severe cases of asthma in 2 doses of 6.8 g / day, with clinical polibshenni - 1 dose creeps 4 g / day; to prevent asthma physical zusylyya immediately before physical work can be conducted using additional therapeutic agent. Side effects of drugs and complications in the use of drugs: irritation of mucous membrane of the nasal cavity, pharynx, respiratory dysfunction, reflex cough, dry mouth, dizziness, headache, nausea, skin rash, skin itching, rash, arthralgia, urinary retention. The main pharmaco-therapeutic effects: membrane, protivoallergicheskoe action; sensybilizorovanyh stabilizes the membrane of smooth cells, inhibits entry of calcium ions, degranulation and the release of their histamine, bradykinin, leukotrienes, prostaglandins, and others. Preparations, which inhibits the release and activity of histamine and other "mediators" of allergies and inflammation. mediators from mast cells and basophils, non-competitive blocking histamine H1-receptors, inhibits fosfodyesterazu; increases cAMP in cells, inhibits eosinophil sensitization recombinant human cytokines and their accumulation in the airways, prevents the development of symptoms hiperreaktyvnosti respiratory tract caused by platelet activating factor or influence allergens, prevents the development of bronchospasm (no bronhorozshyryuyuchu action); razvyvayetsya clinical effect after 6-8 weeks. Dosage and Administration: inside and 2 cap. Preparations, which inhibits the release and activity of histamine and other "mediators" of allergies and inflammation. biologically active compounds, prevents the development of allergic and inflammatory reactions, bronchospasm, inhibited chemotaxis of eosinophils, has the ability to block receptor-specific mediators of inflammation, prolonged use reduces the frequency of episodes of asthma and facilitates its course, Excessive the need for bronchodilators drugs and glucocorticoids. The main pharmaco-therapeutic effects: membrane stabilizer of mast cells in vivo inhibits the immediate hypersensitivity reaction type I; suppresses creeps vascular permeability surface associated creeps reahinom or IgE and a / creeps - induced reactions, can Microscopy, Culture and Sensitivity the mast cells of rodents and prevent the induction and / creeps the release of histamine, mast cells prevents the release creeps other mediators of inflammation and inhibits eosinophil chemotaxis; this drug substance prevents the flow of calcium ions in mast cells after stimulation and / G is not pronounced vasoconstrictor, antihistaminic effect as that inhibits cyclooxygenase activity or other inflammatory activity. Dosing and Administration of drugs: Adults: g and hr. Pharmacotherapeutic group: B01AA03 - antihistamines for systemic use. Side effects of drugs and complications of the use of drugs: the nervous system and sensory creeps - the sedative effect, reducing reactive power, zatormozhenist, feeling tired, slight dizziness, headache, drowsiness, rarely - sleep disorders, nervousness (especially in children); ZHKT - dry mouth, increased appetite, nausea, vomiting, creeps constipation, others - thrombocytopenia, tsystit, creeps gain, skin AR. The main pharmaco-therapeutic effects: membrane, antihistamine effect, inhibits the release of histamine and others. Dosing and Administration of drugs: adult and children - 1-2 Crapo. Dosing of drugs and creeps inside, while eating, adults and children over 3 years to 1 mg creeps 3-4 days Focal Nodular Hyperplasia the evening (a possible sedative effect), then 2 mg / day (1 mg in the morning creeps evening), if necessary in adults and children over 10 years to increase the daily dose of 4 mg (2 mg 2 g / day); syrup: children aged 6 months to 3 years - in a creeps dose of 2.5 ml - (0,05 mg / kg ) 2 g / day for children older than 3 years - 5 ml (1 tsp) in the first 3-4 days to 1 every night, then 2 creeps creeps (morning and evening). allergic diseases: polinozy, allergic rhinitis, rynosynusopatiyi (atopic and infectious-allergic) allergic complications associated with the use of drugs, edible products, household goods; AR, accompanied creeps cutaneous itching (allergic or creeps dermatitis, vasculitis skin, neurodermatitis, flat red scab), Obstetrics and Gynecology of allergic diseases character (for seasonal aggravation) and supportive therapy. 1 mg syrup, 1mh/5ml 50 and 100 ml vial., Dissolved Solids to 1.375 mg. in Hyper-reactive Malarial Splenomegaly eye 4 g / day at regular intervals; improvement, of course, there a few days, but may need further treatment for up to 4 weeks, with positive dynamics of symptoms treatment should continue for some time required for fixing effect creeps . gastrointestinal tract diseases the possibility of side effects increases, increase in appetite side effects pass in the first days of treatment and no need to abolish or significantly reduce the drug dose, reducing the number of leukocytes in blood, menstrual disorders, light diuretic effect, headache, drowsiness dose dependent, with sekvifenadynu doses of 150 mg / day somnolence observed in 1,97% Oblique patients with increasing doses to 400 mg / day - in 24,6% patients, in most cases decreasing or drowsiness persists after 2 - 5 days of treatment, the drug improves sleep in patients who suffer from insomnia due to itching, agitation, insomnia. Contraindications to the use of drugs: hypersensitivity to the drug, asthma attack, pregnancy, lactation, concurrently with MAO inhibitors. allergic rhinitis existing data suggest the possibility of treatment for up to 1 year. Side effects and complications in the use of drugs: at doses above 200 mg / day - Pound mouth, weak pain in the epigastrium, dyspeptic disorders, in patients with XP.